Gonorrhea is a sexually transmitted infection (STI) that may be detected on regular visits at the local sexual health or genitourinary medicine (GUM) clinic for a sexual health test. Early diagnosis and detection of gonorrhoea is important since it may cause long term complications in both men and women. Further early infections are easier to treat using antibiotics but later complications are more difficult to treat. Since almost half of infected women and around one in 10 men do not show any symptoms but may be transmitting the infection to their sexual partners and possibly new born babies, it is important that those at risk get tested regularly. For detection, a swab is used to collect samples of the discharge from the cervix or vagina of the tested woman. In men a swab is used to collect a sample from the entrance of the urethra or they may be asked to provide a urine sample. Those with suspected infections elsewhere need to be tested from their rectum or throat. Those with conjunctivitis are examined and samples of their eye discharge are taken. Researchers from UCLA have developed a laboratory test that helps physicians determine which people with gonorrhea may be more treatable with an antibiotic that has not been recommended since 2007 because of concerns that the resistance to the drug was growing. Gonorrhea has developed increasing resistance to all current antibiotics. Due to the spread of multi-drug resistant gonorrhea, health authorities have declared it one of the top-three urgent threats to public health. Ciprofloxacin was used to combat the sexually transmitted infection until 2007, when the Centers for Disease Control and Prevention stopped recommending its use after gonococcal infections developed resistance to it. Nevertheless, about 80 percent of gonorrhea infections in the United States, however, could be treated with ciprofloxacin. Scientists have been trying to determine how to better identify cases for targeted use of ciprofloxacin therapy, reducing the need to use the antibiotic ceftriaxone and risking increased resistance to that drug. Gonorrhea's resistance rate to ceftriaxone is currently less than 1 percent.
May 21, 2018. Penicillin was no longer effective, but ciprofloxacin was now the recommended treatment and it required only one dose. In King's eyes, getting. Aug 17, 2018. Request PDF on ResearchGate Single-Dose Ciprofloxacin for the Treatment of Uncomplicated Gonorrhea Antibiotic therapy for Neisseria.