Duloxetine hydrochloride is a type of antidepressant called a serotonin and noradrenaline reuptake inhibitor (SNRI). It works by enhancing the activity of the neurotransmitters serotonin and noradrenaline in the brain. Neurotransmitters are natural body chemicals that act as chemical messengers between the nerve cells. Serotonin and noradrenaline are neurotransmitters known to be involved in regulating emotions, mood and behaviour, among other things. In depression and anxiety disorders less serotonin and noradrenaline than normal is released from nerve cells in the brain. Duloxetine works by stopping the serotonin and noradrenaline that has been released from being reabsorbed back into the nerve cells in the brain. This helps to prolong their effects and over time this helps to lighten mood and relieve depression. Duloxetine is also used to treat fibromyalgia (muscle pain and stiffness) and chronic (long-lasting) pain that is related to muscles and bones. Duloxetine belongs to a group of medicines known as selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). These medicines are thought to work by increasing the activity of chemicals called serotonin and norepinephrine in the brain. This medicine is available only with your doctor's prescription.
Duloxetine Find the most comprehensive real-world treatment information on Duloxetine at PatientsLikeMe. 3212 patients with fibromyalgia, multiple sclerosis. Jan 3, 2014. Review question. Does duloxetine work to treat pain generated by nerves when they have been damaged in disease, or the pain caused by.