In some cases, health care professionals may use the trade name deltasone or other names liquid pred or meticorten or orasone when referring to the generic drug name prednisone. Liquid pred and meticorten and orasone are other names for prednisone. Drug type: Prednisone has many uses in the treatment of cancer. (For more detail, see "How this drug works" section below). This list includes common and less common side effects for individuals taking prednisone. Side effects that are very rare, occurring in less than 10% of patients, are not listed here. However, you should always inform your health care provider if you experience any unusual symptoms. You will be checked regularly by your health care professional while you are taking prednisone, to monitor side effects and check your response to therapy. Prednisolone acetate ophthalmic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile ophthalmic suspension and used to reduce swelling, redness, itching, and allergic reactions affecting the eye. Although there are no major human studies of prednisolone use in pregnant women, studies in several animals show that it may cause birth defects including increase cleft palate. Prednisolone should be used in pregnant women when benefits outweigh the risks and children born from mothers using prednisolone during pregnancy should be monitored for impaired adrenal function. Prednisolone is found in breast milk of mothers taking prednisolone. As a glucocorticoid, the lipophilic structure of prednisolone allows for easy passage through the cell membrane where it then binds to its respective glucocorticoid receptor (GCR) located in the cytoplasm. Upon binding, formation of the GC/GCR complex causes dissociation of chaperone proteins from the glucocorticoid receptor enabling the GC/GCR complex to translocate inside the nucleus. Once inside the nucleus, the homodimer GC/GCR complex binds to specific DNA binding-sites known as glucocorticoid response elements (GREs) resulting in gene expression or inhibition. Complex binding to positive GREs leads to synthesis of anti-inflammatory proteins while binding to negative GREs block the transcription of inflammatory genes.
Prednisone is used alone or with other medications to treat the symptoms of low corticosteroid levels (lack of certain substances that are usually produced by the body and are needed for normal body functioning). Prednisone is also used to treat other conditions in patients with normal corticosteroid levels. These conditions include certain types of arthritis; severe allergic reactions; multiple sclerosis (a disease in which the nerves do not function properly); lupus (a disease in which the body attacks many of its own organs); and certain conditions that affect the lungs, skin, eyes, kidneys blood, thyroid, stomach, and intestines. Prednisone is also sometimes used to treat the symptoms of certain types of cancer. Prednisone is in a class of medications called corticosteroids. It works to treat patients with low levels of corticosteroids by replacing steroids that are normally produced naturally by the body. It works to treat other conditions by reducing swelling and redness and by changing the way the immune system works. Anabolic steroids are very useful in treating patients with severe burns that require assistance regenerating tissue, patients infected with the HIV virus who have lost significant weight, patients who have intestinal diseases that inhibit their ability to absorb food, and cancer patients who are losing weight and have appetite loss as a result of chemotherapy. Prednisone is sometimes part of the treatment plan for various types of lymphomas, leukemia, and bronchitis. It is also sometimes used to suppress the immune system of individuals who have organ transplants to lessen the chances of the body rejecting the new organ. The drug has significant medical utility, and it is not a drug that is highly sought after by bodybuilders, athletes, etc., because it is not an anabolic steroid. Prednisone is typically taken orally, but corticosteroids like prednisone can be used in topical medications. The side effect profile of prednisone is relatively benign, and few individuals experience side effects. According to the Food and Drug Administration (FDA), the most common side effects of prednisone include: Although there are side effects associated with the use of any medication, prednisone is typically well tolerated in most individuals.
Apo-Prednisone Prednisone belongs to the group of medications called corticosteroids. It is used to treat a number of conditions. It is more commonly used to treat. Nov 15, 2015. Prednisone is used alone or with other medications to treat the symptoms of low corticosteroid levels lack of certain substances that are usually.