Update to CDC’s Sexually Transmitted Diseases Treatment Guidelines, 2010: Oral cephalosporins no longer a recommended treatment for gonococcal infections. CDC reporters del Rio and colleagues write in MMWR: 1. Update to CDC’s Sexually Transmitted Diseases Treatment Guidelines, 2010: Oral cephalosporins no longer a recommended treatment for gonococcal infections. gonorrhoeae by culture is declining rapidly because of the widespread use of NAATs for diagnosing gonorrhea. Unfortunately, the capacity of US laboratories to isolate N. All positive cultures for test-of-cure should undergo phenotypic antimicrobial susceptibility testing. If the NAAT is positive, make every effort to perform a confirmatory culture. The ideal test-of-cure is performed with culture or, if culture is not readily available, with a nucleic acid amplification testing (NAAT). Many antibiotics are contraindicated in certain patient groups (e.g., children, pregnant or lactating women). In the case of severe infections, early initiation of one or more antibiotics without waiting for a microbiological confirmation is indicated (empirical antibiotic therapy), with the aim of targeting the most likely pathogen(s). Because of widespread use of antibiotics (often misuse!
Beta-lactam antibiotics include penicillins, cephalosporins and related compounds. As a group, these drugs are active against many gram-positive, gram-negative and anaerobic organisms. Information based on “expert opinion” and antimicrobial susceptibility testing supports certain antibiotic choices for the treatment of common infections, but less evidence-based literature is available to guide treatment decisions. Evidence in the literature supports the selection of amoxicillin as first-line antibiotic therapy for acute otitis media. Alternative drugs, such as amoxicillin-clavulanate, trimethoprim-sulfamethoxazole and cefuroxime axetil, can be used to treat resistant infections. Penicillin V remains the drug of choice for the treatment of pharyngitis caused by group A streptococci. Inexpensive narrow-spectrum drugs such as amoxicillin or trimethoprim-sulfamethoxazole are first-line therapy for sinusitis. Therapy addressing specific symptoms is the mainstay for most upper respiratory infections (URIs). Most URIs are self-limited viral infections that resolve without prescription drugs. Recognizing viral and bacterial diseases for which specific therapy is available is important. Awareness of local trends in prevalent organisms and local resistance patterns is key. Antibacterial therapy is appropriate for patients with any of the following: The US Food and Drug Administration (FDA) has warned that azithromycin may lead to QT interval prolongation and torsades de pointes. The FDA notes that "health care professionals should consider the risk of fatal heart rhythms with azithromycin when considering treatment options for patients who are already at risk for cardiovascular events." These include patients with known QT interval prolongation, torsades de pointes, congenital long QT syndrome, bradyarrhythmias, or uncompensated heart failure. Patients with herpes simplex virus (HSV) infection or gonococcal upper airway disease also benefit from specific treatment.
Learn about the potential side effects of Ceftin cefuroxime. Includes common and rare side effects information for consumers and healthcare professionals. History and Etymology for ceftriaxone. cef-alteration of cephalosporin + -triaxone, of unknown origin