Current Concepts in the Management of Congestive Heart Failure Heart failure is often the outcome for a variety of diseases in cats and dogs, with the exceptions of congenital disease (e.g., PDA) or certain acquired diseases, like taurine deficiency and idiopathic pericarditis. There is no cure for heart failure, therefore, treatment is determined by improving clinical signs and improving the quality of life. Treatment options may vary based on the underlying type of disease (e.g., hypertrophic cardiomyopathy versus chronic valvular disease) and it may be more essential to treat the body’s response to the failing heart rather than the appearance of the heart itself. Verifying congestive heart failure (CHF) has been done by historical and physical findings, as well as, thoracic radiographs (Figure 1), NT-pro BNP testing and echocardiography. CHF is treated with a combination of diuretics, an angiotensin-converting enzyme inhibitor, pimobendan, and dietary management. Angiotensin-Converting-Enzyme Inhibitors: Angiotensin-converting-enzyme (ACE) inhibitors are commonly used in the management of CHF. The use of inhibitors is based on the knowledge that the renin-angiotensin-aldosterone axis is stimulated in dogs and cats with CHF. If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware. If you are at an office or shared network, you can ask the network administrator to run a scan across the network looking for misconfigured or infected devices. Another way to prevent getting this page in the future is to use Privacy Pass. Check out the browser extension in the Firefox Add-ons Store.
Diuretics are used to remove inappropriate water volume in animals with edema or volume overload, correct specific ion imbalances, and reduce blood pressure and pulmonary capillary wedge pressure (see Table: Dosages of Diuretics). They are classified by their mechanism of action as loop diuretics, carbonic anhydrase inhibitors, thiazides, osmotic diuretics, and potassium-sparing diuretics. The efficacy and use of each class of diuretic depends on the mechanism and site of action. Patterns of electrolyte excretion vary between classes, whereas maximal response is the same within a class. Therefore, if one drug within a class is ineffective, a different drug from the same class will likely be ineffective as well. Combining diuretics from different classes can lead to additive and potentially synergistic effects. induces beneficial hemodynamic effects before the onset of diuresis. Vasodilation increases renal blood flow, thereby increasing renal perfusion and lessening fluid retention. Furosemide is a diuretic, which is used to treat congestive heart failure, pulmonary edema, kidney disease, high blood pressure and edema. This drug is essentially a ‘loop diuretic drug’, which works on a specific area of the kidney known as Henle’s loop. Furosemide restricts the increased absorption of chloride, sodium, potassium and water into the kidney, thus supporting the removal of excessive fluid. Furosemide significantly lowers accumulation of fluid and prevents the occurrence of edema. Certain precautions should be taken prior to administering Furosemide to the pet. The drug should not be prescribed for animals that are allergic to it. Never use it in pets that have disorders associated with electrolyte imbalance.
It looks like you are trying to access 1800Pet Meds from a country in the EU. Due to the GDPR we are unable to accept your business at this time. Please check back from time to time for updates on our policy. If you are in the United States or Canada and believe you have reached this page in error, make sure to disable any VPN or Proxy services you might be using to access our site. If you are seeking Investor information, you can find our Investor Site by following this link. Dogs and cats: Congestive heart failure (CHF), pulmonary edema, uremia, hyperkalemia, hypertension. Horses: Exercise induced pulmonary hemorrhage, acute renal failure, edema due to a variety of causes. Furosemide is a potent loop-diuretic that acts within the kidney to produce a dose-dependent increase in urine output with increased urinary excretion of sodium, potassium, calcium, chloride, magnesium, hydrogen, ammonium, and bicarbonate. Furosemide increases blood flow to the kidney, and causes a transient increase in the glomerular filtration rate. It has no effect on carbonic anhydrase and does not have an antagonistic effect on aldosterone. Although the urinary loss of electrolytes is substantial, they are usually replaced within 24 hours by re-absorption by the kidneys and within the GI tract. Furosemide may be administered orally, intramuscularly, subcutaneously, or intravenously.
The latest Tweets from MSU @michiganstateu. The official Twitter account for Michigan State University. #SpartansWill. East Lansing, MI USA Ref But in cats, it is disease of the heart muscle itself, cardiomyopathies, that are. Occasionally, particularly at high doses, furosemide can lead to too much.